Many people know hepatitis B big three positive and hepatitis B small three positive, but the difference between the two is not very clear, or even do not know whether they are big three positive or small three positive. In fact, the difference between hepatitis B big three positive and hepatitis B small three positive is very obvious. This article will introduce in detail the difference between hepatitis B big three positive and hepatitis B natural and unrestrained.
1. The difference between big three positive and small three positive lies in the difference in the results and significance of two half and half tests of hepatitis B
The two halves of hepatitis B refer to hepatitis B surface antigen, hepatitis B surface antibody, hepatitis B e antigen, hepatitis B e antibody, and hepatitis B core antibody. Usually, those who are positive (or+) for items 1, 3, and 5 are referred to as the "Big Three Yangs", while those who are positive (or+) for items 1, 4, and 5 are referred to as the "Small Three Yangs".
The positive hepatitis B e antigen of Big Three Yang indicates that hepatitis B virus is actively replicating, so its infectivity is also strong.
The positive hepatitis B e antibody of Xiao Sanyang indicates that the replication of hepatitis B virus has been inhibited and its infectivity has become weaker.
2. The difference between big three positive and small three positive is also slightly different in hepatitis B virus DNA detection results
The patients with hepatitis B "Big Three Positive" are more likely to be positive for HBV-DNA, indicating that there are many viruses in the body, and the virus replication is active and infectious. But if the liver function is normal and there are no obvious symptoms, antiviral treatment is not recommended because the antiviral effect is poor at this time. If accompanied by abnormal liver function or inflammatory damage on liver biopsy to a certain extent, or if there are obvious symptoms, treatment is needed. At the same time, the occurrence of liver fibrosis and cirrhosis should be checked. Older patients with a longer course of disease should pay attention to prevention.
Most of the patients with hepatitis B with minor three positives are negative for HBV-DNA, indicating that the number of viruses in the body is small. Sometimes there may be situations where the virus cannot be detected. Although there is a possibility that the virus has been completely eliminated, it cannot be ruled out that there may still be a small amount of virus, so there is still a possibility of transmission. Virus replication is inhibited and has low infectivity. If Xiao San Yang is accompanied by HBV-DNA positivity, it is suspected that there may be a virus mutation. It is recommended to undergo liver function, ultrasound and other tests to determine the condition, randomly change the treatment plan, and prevent liver fibrosis and other liver damage.
3. The difference between Da San Yang and Xiao San Yang: blind obedience ideology
Although there is no obvious difference between the big three positive and the small three positive in terms of disease condition, people are more likely to pay attention to the big three positive of hepatitis B in terms of cognition, because the big three positive of hepatitis B is relatively high in infectivity. Although there is no obvious harm to the patients themselves, it will create psychological pressure on the surrounding people and fear of being infected. Therefore, patients with triple positive are also more concerned about their own health. So many diseases such as cirrhosis and liver cancer are easier to detect in the early stages. However, due to its low infectivity, Xiao San Yang is often overlooked, and patients themselves feel a sense of relief. Late stage liver disease is relatively difficult to detect, resulting in more serious consequences than the Big Three Yang. I don't know which comrade has a point: Big San Yang is vicious, Little San Yang is sinister. Therefore, we should treat all three types of yang equally, pay attention to ourselves at all times, seize the opportunity, and actively seek treatment.
This article introduces in detail the difference between hepatitis B big three positive and hepatitis B small three positive. If you are a patient with hepatitis B, or you think hepatitis B, you'd better carefully refer to the content of this article to determine what is going on with hepatitis B, the big three positive and the small three positive.