There are many reasons that can affect maternal and fetal mortality, and gestational hypertension is one of them. This disease seriously threatens the health of both mother and baby, but many new mothers do not know what gestational hypertension is and what causes it? Next, friends, let's follow the editor to learn about gestational hypertension.
What is gestational hypertension
Pregnancy induced hypertension is a common obstetric disease, accounting for 5% -10% of all pregnancies. It causes approximately 10-16% of all pregnancy related deaths and is the second leading cause of maternal mortality. Pregnancy induced hypertension can be divided into five categories based on the underlying causes and degree of organ damage, namely pregnancy induced hypertension, preeclampsia, eclampsia, chronic hypertension with preeclampsia, and chronic hypertension. The main symptoms include hypertension, proteinuria, edema, etc.
The etiology of gestational hypertension
1. Abnormal invasion of nourishing cells. It may be an important factor in the onset of preeclampsia. The patient's nourishing cells invade the spiral arterioles incompletely, and the spiral arterioles in the uterine muscle layer do not undergo remodeling. The abnormally narrow spiral artery reduces placental perfusion and hypoxia, ultimately leading to the occurrence of preeclampsia.
2. Abnormal immune regulatory function. The loss or imbalance of maternal immune tolerance to placental and fetal antigens derived from the father is an important component of the etiology of preeclampsia.
3. Damage to vascular endothelium. Oxidative stress, anti angiogenic and metabolic factors, as well as other inflammatory mediators, can lead to endothelial damage and trigger preeclampsia.
4. Genetic factors. Pre eclampsia is a multifactorial and polygenic disease with familial genetic tendency: the incidence rate of pre eclampsia in the daughters of mothers with pre eclampsia is 20%~40%; The incidence rate of preeclampsia in sisters of women with preeclampsia was 11%~37%; The incidence rate of preeclampsia in sisters of women with preeclampsia in twins is 22%~47%. But so far, its genetic pattern is still unclear.
5. Nutritional factors. Lack of vitamin C can increase the risk of developing preeclampsia eclampsia.
Alright, through the above content, I believe friends have gained some knowledge about gestational hypertension. Since gestational hypertension is so scary, friends preparing for pregnancy should consider it carefully. To eliminate the opportunity of gestational hypertension, they need to first understand the causes of this disease. Finally, I hope all friends are healthy.
