The editor will first briefly introduce the information of type T lymphoma, which is characterized by the destruction of lymph node structure, diffuse proliferation of tumor cells, tightly arranged cells but not adhering to each other, and frequent nuclear fission. T-lymphoblastic lymphoma (TLBL) is rare, with unique clinical manifestations, poor prognosis, and rarely involving the skin. So what are the initial symptoms of type T lymphoma? Let the editor popularize science for everyone.
What are the early symptoms of lymphoma
1. Lymph nodes and lymphoid tissue onset
Superficial lymph node onset is predominant, and HD is more common than NHL. The most affected lymph nodes are in the neck, followed by the armpits and groin. Generally painless, with progressive swelling and moderate hardness. In the early stage, it can be active, but in the late stage, adhesion and multiple swollen lymph nodes often occur and merge into lumps. Some HD patients may experience temporary pause or even reduction in lymph node enlargement at a certain time, leading to misdiagnosis as lymphadenitis or lymph node tuberculosis.
The onset of deep lymph nodes is more common, with mediastinal lymph nodes being the most common. Enlarged lymph nodes can compress the superior vena cava, causing superior vena cava syndrome. It can also compress the trachea, esophagus, and recurrent laryngeal nerve, leading to symptoms such as difficulty breathing, swallowing, and hoarseness. Mediastinal NHL complicated with lymphosarcoma cell leukemia is more common. However, the first onset of mediastinal HD in young women is often nodular sclerosis, and they are often dissatisfied with the treatment response.
Malignant lymphoma originating from retroperitoneal lymph nodes, with NHL being the most common, can cause long-term, unexplained fever, making clinical diagnosis difficult.
Lymphoma originating from the pharyngeal lymphatic ring is more common in NHL and often accompanied by subphrenic invasion. Symptoms include sore throat, foreign body sensation, difficulty breathing, and hoarseness.
2. Extranodal onset
Except for lymphoid tissue, the disease can occur in any part of the body, with primary gastrointestinal lymphoma being the most common. Lymphoma of the stomach and high small intestine may present with symptoms such as upper abdominal pain and vomiting. Small intestinal lymphoma is more common in the ileocecal area, often accompanied by chronic diarrhea, fat diarrhea, and intestinal obstruction.
3. Systemic symptoms
Often experiencing general weakness, emaciation, loss of appetite, night sweats, and irregular fever. A small number of HD patients may experience periodic fever.
The above are the three main early symptoms of type T lymphoma. Lymphoma is a major threat to human life and health, so when patients experience the above symptoms, they should seek medical attention promptly.
