Idiopathic thrombocytopenic purpura is caused by the disruption of the human immune system, which leads to the destruction of platelets and the inability to complete its own systemic tasks. This kind of problem is actually a significant issue worth noting. You must go to the hospital for treatment and hospitalization if necessary. If you feel discomfort in this area, you should pay attention and not treat it as nothing. Next, let's take a look at the care for idiopathic thrombocytopenic purpura with the editor.
1. Symptoms and signs: This disease is common in children of all ages, mostly in children aged 1-5 years old. There is no difference in the number of cases between males and females, with a higher incidence in spring. Acute type children often have a history of acute viral infections, such as upper respiratory tract infections, mumps, chickenpox, rubella, measles, infectious mononucleosis, etc., 13 weeks before onset. It is also occasionally seen after vaccination with attenuated measles vaccine or tuberculosis vaccine. Most children have no symptoms before onset, and some may experience fever. The prominent manifestation of the child is spontaneous skin and mucosal bleeding, mostly needle sized intradermal or subcutaneous bleeding points, or bruising and purple epilepsy, with rare skin bleeding spots and hematomas.
2. After viral infection, the body produces corresponding antibodies, which can cross react with the platelet membrane, causing damage to the platelets and clearing them by the mononuclear macrophage system. In addition, after viral infection, antigen antibody complexes formed in the body can attach to the surface of platelets, making them easy to be engulfed and destroyed by the mononuclear macrophage system. Shortening the lifespan of platelets, leading to a decrease in platelets, and an increase in the level of platelet associated antibodies (PAIgG) in the patient's serum, with the acute type showing a more significant increase in antibody levels than the chronic type.
3. The content of PAIgG is negatively correlated with platelet count: the higher the PAIgG, the lower the platelet count. However, there are also a few patients whose PAIgG content does not increase. It is now known that platelets and megakaryocytes have common antigenicity, and antiplatelet antibodies also act on megakaryocytes in the bone marrow, leading to megakaryocyte maturation disorders. The generation and release of megakaryocytes are seriously affected, further reducing platelets.
The above is the information provided by the editor regarding the care of idiopathic thrombocytopenic purpura. This kind of problem is more professional, and it is better to go to a professional hospital after the problem occurs. Try not to think that you are okay. It is best to have a physical examination every year in this regard to ensure that there are no issues with one's blood and facial hair. Don't be afraid of this problem, the development of medicine will definitely lead to recovery. I hope the editor's organization is helpful to you.
