Pregnant mothers need to pay attention to many things during pregnancy. Of course, family members will take good care of pregnant mothers, but scientific examinations are also essential, so there is a monthly routine prenatal examination for pregnant mothers. The value of progesterone during prenatal examination is also a special concern for everyone. Next, let's take a look at the six tests for progesterone with the editor.
1. Testosterone (T): 50% of testosterone in women's bodies is converted from peripheral androstenedione, about 25% is secreted by the adrenal cortex, and only 25% comes from the ovaries. The main function is to promote the development of the clitoris, labia, and pubic mound. It has an antagonistic effect on estrogen and has a certain impact on systemic metabolism. The normal blood T concentration in females is 0.7-3.1 nmol/L. A high blood T value, known as hypertestosterone, can cause infertility. When suffering from polycystic ovary syndrome, the blood T value also increases. According to clinical manifestations, other hormones may be measured as necessary.
2. Estradiol (E2): Secreted by ovarian follicles, its main function is to promote the transformation of the endometrium into a proliferative phase and facilitate the development of female secondary sexual characteristics. The concentration of blood E2 is 48-521 picomoles/liter in the pre ovulation period, 70-1835 picomoles/liter in the ovulation period, and 272-793 picomoles/liter in the post ovulation period. Low values are seen in ovarian dysfunction, premature ovarian failure, and Sheehan syndrome.
3. Progesterone (P): secreted by the corpus luteum of the ovary, its main function is to promote the transition of the endometrium from the proliferative phase to the secretory phase. The blood P concentration is 0-4.8 nmol/L before ovulation and 7.6-97.6 nmol/L in the late stage of ovulation. The low blood P value in the late stage of ovulation is seen in luteal insufficiency, ovulatory dysfunctional uterine bleeding, etc.
4. Luteinizing hormone (LH): A glycoprotein hormone secreted by basophils in the anterior pituitary gland, mainly promoting ovulation. Under the synergistic effect of FSH, it forms the corpus luteum and secretes progesterone. The concentration of LH in the blood is 2-15mIU/ml during the pre ovulation period, 30-100mIU/ml during the ovulation period, and 4-10mIU/ml during the post ovulation period. The normal value during non ovulation period is usually 5-25mIU/ml. A level below 5mIU/ml indicates insufficient gonadotropin function, which is seen in Sheehan syndrome. If high FSH is combined with high LH, ovarian failure is already very certain and no further examinations are necessary. LH/FSH ≥ 3 is one of the criteria for diagnosing polycystic ovary syndrome.
5. Prolactin (PRL): Secreted by one of the eosinophils in the anterior pituitary gland, prolactin is a simple protein hormone that primarily functions to promote breast hyperplasia, milk production, and lactation. During non lactation, the normal range of blood PRL is 0.08-0.92 nmol/L. Higher than 1.0 nmol/L is considered hyperprolactinemia, and excessive prolactin can inhibit the secretion of FSH and LH, suppress ovarian function, and inhibit ovulation.
6. Follicle stimulating hormone (FSH): A glycoprotein hormone secreted by basophils in the anterior pituitary gland, whose main function is to promote the development and maturation of ovarian follicles. The concentration of blood FSH is 1.5-10 mIU/ml in the pre ovulation period, 8-20 mIU/ml in the ovulation period, and 2-10 mIU/ml in the post ovulation period. Generally, the normal value is 5-40mIU/ml. Low FSH levels are seen during estrogen and progesterone treatment, as well as in Sheehan syndrome. FSH is commonly found in premature ovarian failure, ovarian insensitivity syndrome, primary amenorrhea, and other conditions.
The above is the data compiled by the editor regarding the six tests for progesterone. Based on the above information, the editor has organized the content and values of six inspection items, as well as their specific meanings. You can choose the content you need from the above information. I hope the editor's organization is helpful to you.