The occurrence of miscarriage is not desirable for anyone, as it causes great damage to the bodies of female friends and even affects their work and life. So some female friends want to know what causes miscarriage? Let's all learn about it with me.
1. Insufficient endocrine function of placenta
In early pregnancy, in addition to the secretion of progesterone by the corpus luteum of the ovary, placental trophoblasts also gradually produce progesterone. After 8 weeks of pregnancy, the placenta gradually becomes the main site for producing progesterone. In addition to progesterone, the placenta also synthesizes other hormones such as β - chorionic gonadotropin, placental lactogen, and estrogen. During early pregnancy, the hormone levels mentioned above decrease, making it difficult to continue the pregnancy and leading to miscarriage.
2. Genetic factors
During early natural miscarriage, embryos with chromosomal abnormalities account for 50% to 60%, mostly due to chromosomal numerical abnormalities, followed by chromosomal structural abnormalities. Abnormal numbers include trisomy, triploidy, and X monomer. Structural abnormalities include chromosome breakage, inversion, deletion, and translocation. Embryos with chromosomal abnormalities mostly end up with miscarriage, and a very small number may continue to develop into fetuses, but some functional abnormalities or combined deformities may also occur after birth. If a miscarriage has occurred, the pregnancy product is sometimes only an empty gestational sac or a degenerated embryo.
3. Immune factors
Pregnancy is like allogeneic transplantation, where there is a complex and unique immunological relationship between the embryo and the mother, which prevents the embryo from being rejected. If both mother and child are immune incompatible, it can cause maternal rejection of the embryo and result in miscarriage. The main immune factors include the father's histocompatibility antigen, fetal specific antigen, blood type antigen, and maternal cell immune regulation disorder.
4. Environmental factors
There are many external adverse factors that affect reproductive function, which can directly or indirectly cause damage to the embryo or fetus. Excessive exposure to harmful chemicals such as arsenic, lead, benzene, formaldehyde, chloroprene, ethylene oxide, and physical factors such as radiation, noise, and high temperatures can all cause miscarriage.
Through the introduction, we have learned about some factors that can cause miscarriage, and all aspects of these factors should be given sufficient attention. If you accidentally have a miscarriage, you need to understand the specific reasons for the miscarriage and take corresponding measures. Don't be sad, female friends who have had an abortion. Pay attention to taking care of your body and lay a good physical foundation for the next pregnancy.
