What is the difference between amniocentesis and non-invasive DNA testing

  There are many examinations that pregnant women need to undergo during pregnancy, and the examination items they need to undergo for different reasons are also different. In addition to some routine examination items, some pregnant women may need to undergo amniocentesis or non-invasive DNA testing for special reasons. So what is the difference between amniocentesis and non-invasive DNA testing?

  

What is the difference between amniocentesis and non-invasive DNA testing1

  1. Non invasive DNA

  This method mainly involves collecting 10 milliliters of peripheral blood from pregnant women to extract free DNA, and using next-generation sequencing technology combined with bioinformatics analysis to test and screen fetal chromosomes. It can accurately screen for the risk of Down syndrome, Patao syndrome, and Edwards syndrome. This examination is suitable for pregnant mothers between 12 and 26 weeks of pregnancy.

  2. Amniocentesis

  This method is mainly a way to conduct further diagnostic tests on the results of Down syndrome screening tests, based on the premise that the fetus has a high risk.

  Mainly guided by ultrasound, a thin and long needle is inserted through the pregnant mother's abdomen and uterine wall, entering the amniotic fluid cavity to extract the amniotic fluid. After comprehensive examination of the amniotic fluid, the preliminary diagnosis results are checked again. Generally, pregnant women with high-risk results from Tang screening need to undergo another amniocentesis examination. This examination is suitable for pregnant mothers between 16 weeks and 22 weeks plus 6 days of pregnancy.

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