What is low platelet count in children

  Platelets are very important hematopoietic cells that play a role in coagulation. When a person suffers from trauma, platelets aggregate to stop bleeding. Thrombocytopenia is a common clinical condition, not a difficult or complicated disease, and can occur in children and adults. So, what is the reason for low platelet count in children?

  

What is low platelet count in children1

  Below are four reasons for low platelet count in children.

  1. Decreased platelet production: Decreased platelet production includes both genetic and acquired types, which are related to factors such as drugs, malignant tumors, infections, ionizing radiation, etc. These factors can promote the proliferation of hematopoietic stem cells. Aplastic anemia and acute leukemia are common blood diseases that can also lead to low platelets in young children.

  2. Immunodeficiency: Pediatric thrombocytopenia may also be caused by immune mechanism defects, also known as immune thrombocytopenia in clinical practice. There are many triggering factors for this disease, including chemical toxins, radiation, ionizing radiation, viral infections, and excessive fatigue.

  3. Drug effects: There are multiple drugs that can cause thrombocytopenia, some of which can cause low or impaired bone marrow regeneration, while others can cause bone marrow regeneration disorders; Some drugs inhibit the action of megakaryocytes.

  4. Maternal factors: If a pregnant woman suffers from thrombocytopenia or uses certain anticoagulant drugs, it can lead to thrombocytopenia in the child after birth. Children may experience widespread bleeding points, and in severe cases, nosebleeds may occur.

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